House: You made a decision.
Patient: I changed my mind.
Patient: Because there are more important things than-
House: Than what? Than your brain? Your abilities? That’s where everything comes from; any meaning in your life, any happiness.
Patient: Not all happiness-
House: [with contempt and anger] He’s already left once. He’s gonna leave you again. You don’t need to depend on people who are gonna let you down. If you do this, you’re a [fishes for the right word, then continues in a biting tone] pathetic hypocrite. Your signature whole life, all your work up until him was a pointless-
Patient: Why are you doing this?
House realizes, then walks out.
Of course, House is describing his relationship with Cuddy.